Sporeamicin A, a new macrolide antibiotic. I. Taxonomy, fermentation, isolation and characterization.
نویسندگان
چکیده
Sporeamicin A, a novel antibiotic, was isolated from the culture filtrate of an actinomycete. The producing organism, strain L53-18, was taxonomically assigned as a species of the genus Saccaropolyspora. The antibiotic was extracted with chloroform and was then purified by crystallization. It was obtained as colorless prisms from ethanolic solutions. Sporeamicin A exhibited a strong UV absorption peak at 276 nm. The molecular formula of sporeamicin A was determined to be C37H63NO12.
منابع مشابه
Sporeamicin A, a new macrolide antibiotic. II. Structure determination.
Structure of a novel antibiotic, sporeamicin A (SRM-A), was determined by a combination of spectroscopic and X-ray crystallographic studies. SRM-A has a unique structure containing a 2,3-dihydro-3-oxofuran moiety as part of a 14-membered macrolide ring.
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عنوان ژورنال:
- The Journal of antibiotics
دوره 45 5 شماره
صفحات -
تاریخ انتشار 1992